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Glioma Grading Clinical and Mutation Features

Gliomas are the most common primary tumors of the brain. They can be graded as LGG (Lower-Grade Glioma) or GBM (Glioblastoma Multiforme) depending on the histological/imaging criteria. Clinical and molecular/mutation factors are also very crucial for the grading process. Molecular tests are expensive to help accurately diagnose glioma patients. In this dataset, the most frequently mutated 20 genes and 3 clinical features are considered from TCGA-LGG and TCGA-GBM brain glioma projects. The prediction task is to determine whether a patient is LGG or GBM with a given clinical and molecular/mutation features. The main objective is to find the optimal subset of mutation genes and clinical features for the glioma grading process to improve performance and reduce costs.